Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells

In this work two acetylene alcohols, compound 1 and compound 2, which were isolated and identified from the sponge Cribrochalina vasculum, and which showed anti-tumor effects were further studied with respect to targets and action mechanisms. Gene expression analyses suggested insulin like growth fa...

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Detalles Bibliográficos
Autores principales: Zovko, Ana, Novak, Metka, Hååg, Petra, Kovalerchick, Dimitry, Holmlund, Teresa, Färnegårdh, Katarina, Ilan, Micha, Carmeli, Shmuel, Lewensohn, Rolf, Viktorsson, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226581/
https://www.ncbi.nlm.nih.gov/pubmed/27384680
http://dx.doi.org/10.18632/oncotarget.10361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226581/
https://www.ncbi.nlm.nih.gov/pubmed/27384680
http://dx.doi.org/10.18632/oncotarget.10361

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