Microvesicle removal of anticancer drugs contributes to drug resistance in human pancreatic cancer cells

High mortality in pancreatic cancer patients is partly due to resistance to chemotherapy. We describe that human pancreatic cancer cells acquire drug resistance by a novel mechanism in which they expel and remove chemotherapeutic drugs from the microenvironment via microvesicles (MVs). Using human p...

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Detalles Bibliográficos
Autores principales: Muralidharan-Chari, Vandhana, Kohan, Hamed Gilzad, Asimakopoulos, Alexandros G., Sudha, Thangirala, Sell, Stewart, Kannan, Kurunthachalam, Boroujerdi, Mehdi, Davis, Paul J., Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226588/
https://www.ncbi.nlm.nih.gov/pubmed/27391262
http://dx.doi.org/10.18632/oncotarget.10395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226588/
https://www.ncbi.nlm.nih.gov/pubmed/27391262
http://dx.doi.org/10.18632/oncotarget.10395

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