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Optogenetic regulation of site-specific subtelomeric DNA-methylation

Telomere length homeostasis, critical for chromosomal integrity and genome stability, is controlled by intricate molecular regulatory machinery that includes epigenetic modifications. Here, we examine site-specific and spatiotemporal alteration of the subtelomeric methylation of CpG islands using op...

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Detalles Bibliográficos
Autores principales: Choudhury, Samrat Roy, Cui, Yi, Narayanan, Anoop, Gilley, David P., Huda, Nazmul, Lo, Chiao-Ling, Zhou, Feng C., Yernool, Dinesh, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226589/
https://www.ncbi.nlm.nih.gov/pubmed/27391261
http://dx.doi.org/10.18632/oncotarget.10394