SUMOylation of PES1 upregulates its stability and function via inhibiting its ubiquitination

PES1 is a component of the PeBoW complex, which is required for the maturation of 28S and 5.8S ribosomal RNAs, as well as for the formation of the 60S ribosome. Deregulation of ribosomal biogenesis can contribute to carcinogenesis. In this study, we showed that PES1 could be modified by the small ub...

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Detalles Bibliográficos
Autores principales: Li, Shujing, Wang, Miao, Qu, Xinjian, Xu, Zhaowei, Yang, Yangyang, Su, Qiming, Wu, Huijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226600/
https://www.ncbi.nlm.nih.gov/pubmed/27409667
http://dx.doi.org/10.18632/oncotarget.10494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226600/
https://www.ncbi.nlm.nih.gov/pubmed/27409667
http://dx.doi.org/10.18632/oncotarget.10494

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