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Developmental Changes in Expression of βIV Spectrin Splice Variants at Axon Initial Segments and Nodes of Ranvier

Axon initial segments (AIS) and nodes of Ranvier are highly specialized axonal membrane domains enriched in Na(+) channels. These Na(+) channel clusters play essential roles in action potential initiation and propagation. AIS and nodal Na(+) channel complexes are linked to the actin cytoskeleton thr...

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Detalles Bibliográficos
Autores principales: Yoshimura, Takeshi, Stevens, Sharon R., Leterrier, Cristophe, Stankewich, Michael C., Rasband, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226651/
https://www.ncbi.nlm.nih.gov/pubmed/28123356
http://dx.doi.org/10.3389/fncel.2016.00304