hGBP-1 Expression Predicts Shorter Progression-Free Survival in Ovarian Cancers, While Contributing to Paclitaxel Resistance

Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance in ovarian cell lines. Forced expression of hGBP-...

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Detalles Bibliográficos
Autores principales: Wadi, Suzan, Tipton, Aaron R., Trendel, Jill A., Khuder, Sadik A., Vestal, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226657/
https://www.ncbi.nlm.nih.gov/pubmed/28090373
http://dx.doi.org/10.4236/jct.2016.713097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226657/
https://www.ncbi.nlm.nih.gov/pubmed/28090373
http://dx.doi.org/10.4236/jct.2016.713097

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