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hGBP-1 Expression Predicts Shorter Progression-Free Survival in Ovarian Cancers, While Contributing to Paclitaxel Resistance
Ovarian cancer is the gynecological cancer with the poorest prognosis. One significant reason is the development of resistance to the chemotherapeutic drugs used in its treatment. The large GTPase, hGBP-1, has been implicated in paclitaxel resistance in ovarian cell lines. Forced expression of hGBP-...
Autores principales: | Wadi, Suzan, Tipton, Aaron R., Trendel, Jill A., Khuder, Sadik A., Vestal, Deborah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226657/ https://www.ncbi.nlm.nih.gov/pubmed/28090373 http://dx.doi.org/10.4236/jct.2016.713097 |
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