Chaperone-Mediated Autophagy Protein BAG3 Negatively Regulates Ebola and Marburg VP40-Mediated Egress

Ebola (EBOV) and Marburg (MARV) viruses are members of the Filoviridae family which cause outbreaks of hemorrhagic fever. The filovirus VP40 matrix protein is essential for virus assembly and budding, and its PPxY L-domain motif interacts with WW-domains of specific host proteins, such as Nedd4 and...

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Detalles Bibliográficos
Autores principales: Liang, Jingjing, Sagum, Cari A., Bedford, Mark T., Sidhu, Sachdev S., Sudol, Marius, Han, Ziying, Harty, Ronald N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226679/
https://www.ncbi.nlm.nih.gov/pubmed/28076420
http://dx.doi.org/10.1371/journal.ppat.1006132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226679/
https://www.ncbi.nlm.nih.gov/pubmed/28076420
http://dx.doi.org/10.1371/journal.ppat.1006132

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