Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

A comprehensive understanding of the regions on HIV-1 envelope trimers targeted by broadly neutralizing antibodies may contribute to rational design of an HIV-1 vaccine. We previously identified a participant in the CAPRISA cohort, CAP248, who developed trimer-specific antibodies capable of neutrali...

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Detalles Bibliográficos
Autores principales: Wibmer, Constantinos Kurt, Gorman, Jason, Ozorowski, Gabriel, Bhiman, Jinal N., Sheward, Daniel J., Elliott, Debra H., Rouelle, Julie, Smira, Ashley, Joyce, M. Gordon, Ndabambi, Nonkululeko, Druz, Aliaksandr, Asokan, Mangai, Burton, Dennis R., Connors, Mark, Abdool Karim, Salim S., Mascola, John R., Robinson, James E., Ward, Andrew B., Williamson, Carolyn, Kwong, Peter D., Morris, Lynn, Moore, Penny L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226681/
https://www.ncbi.nlm.nih.gov/pubmed/28076415
http://dx.doi.org/10.1371/journal.ppat.1006074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226681/
https://www.ncbi.nlm.nih.gov/pubmed/28076415
http://dx.doi.org/10.1371/journal.ppat.1006074

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