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p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration

One of the proteins most frequently found in neuropathological lesions is the ubiquitin binding protein p62 (sequestosome 1). Post-mortem analysis of p62 is a defining diagnostic marker in several neurodegenerative diseases including amyotrophic lateral sclerosis and inclusion body myositis. Since p...

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Detalles Bibliográficos
Autores principales: Jackson, Kasey L., Lin, Wen-Lang, Miriyala, Sumitra, Dayton, Robert D., Panchatcharam, Manikandan, McCarthy, Kevin J., Castanedes-Casey, Monica, Dickson, Dennis W., Klein, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226781/
https://www.ncbi.nlm.nih.gov/pubmed/28076378
http://dx.doi.org/10.1371/journal.pone.0169291