Enhanced Rb/E2F and TSC/mTOR Pathways Induce Synergistic Inhibition in PDGF-Induced Proliferation in Vascular Smooth Muscle Cells

Platelet-derived growth factor (PDGF) plays an essential role in proliferation of vascular smooth muscle cells (VSMCs). The Rb/E2F and TSC/mTOR pathways contribute to the proliferation of VSMCs, but its exact roles in PDGF-induced proliferation are unclear. In this study, we demonstrated the roles o...

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Detalles Bibliográficos
Autores principales: Li, Yue, Li, Xuan, Liu, Jie, Guo, Wei, Zhang, Hongchao, Wang, Jianchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226788/
https://www.ncbi.nlm.nih.gov/pubmed/28076433
http://dx.doi.org/10.1371/journal.pone.0170036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226788/
https://www.ncbi.nlm.nih.gov/pubmed/28076433
http://dx.doi.org/10.1371/journal.pone.0170036

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