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Emerging Bordetella pertussis Strains Induce Enhanced Signaling of Human Pattern Recognition Receptors TLR2, NOD2 and Secretion of IL-10 by Dendritic Cells

Vaccines against pertussis have been available for more than 60 years. Nonetheless, this highly contagious disease is reemerging even in countries with high vaccination coverage. Genetic changes of Bordetella pertussis over time have been suggested to contribute to the resurgence of pertussis, as th...

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Detalles Bibliográficos
Autores principales: Hovingh, Elise S., van Gent, Marjolein, Hamstra, Hendrik-Jan, Demkes, Marc, Mooi, Frits R., Pinelli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226795/
https://www.ncbi.nlm.nih.gov/pubmed/28076445
http://dx.doi.org/10.1371/journal.pone.0170027