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IFNγ Regulates Activated Vδ2+ T Cells through a Feedback Mechanism Mediated by Mesenchymal Stem Cells

γδ T cells play a role in a wide range of diseases such as autoimmunity and cancer. The majority of circulating human γδ T lymphocytes express a Vγ9Vδ2+ (Vδ2+) T cell receptor (TCR) and following activation release pro-inflammatory cytokines. In this study, we show that IFNγ, produced by Vδ2+ cells,...

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Detalles Bibliográficos
Autores principales: Fechter, Karoline, Dorronsoro, Akaitz, Jakobsson, Emma, Ferrin, Izaskun, Lang, Valérie, Sepulveda, Pilar, Pennington, Daniel J., Trigueros, César
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226805/
https://www.ncbi.nlm.nih.gov/pubmed/28076364
http://dx.doi.org/10.1371/journal.pone.0169362