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Sensitization of TRPA1 by Protein Kinase A

The TRPA1 ion channel is expressed in nociceptive (pain-sensitive) somatosensory neurons and is activated by a wide variety of chemical irritants, such as acrolein in smoke or isothiocyanates in mustard. Here, we investigate the enhancement of TRPA1 function caused by inflammatory mediators, which i...

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Detalles Bibliográficos
Autores principales: Meents, Jannis E., Fischer, Michael J. M., McNaughton, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226813/
https://www.ncbi.nlm.nih.gov/pubmed/28076424
http://dx.doi.org/10.1371/journal.pone.0170097