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Sensitization of TRPA1 by Protein Kinase A
The TRPA1 ion channel is expressed in nociceptive (pain-sensitive) somatosensory neurons and is activated by a wide variety of chemical irritants, such as acrolein in smoke or isothiocyanates in mustard. Here, we investigate the enhancement of TRPA1 function caused by inflammatory mediators, which i...
Autores principales: | Meents, Jannis E., Fischer, Michael J. M., McNaughton, Peter A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226813/ https://www.ncbi.nlm.nih.gov/pubmed/28076424 http://dx.doi.org/10.1371/journal.pone.0170097 |
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