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Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells

PC12 cells are a well-established model to study how differences in signal transduction duration can elicit distinct cell behaviors. Epidermal growth factor (EGF) activates transient ERK signaling in PC12 cells that lasts 30–60 min, which in turn promotes proliferation; nerve growth factor (NGF) act...

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Detalles Bibliográficos
Autores principales: Adams, Kenneth W., Kletsov, Sergey, Lamm, Ryan J., Elman, Jessica S., Mullenbrock, Steven, Cooper, Geoffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226839/
https://www.ncbi.nlm.nih.gov/pubmed/28076410
http://dx.doi.org/10.1371/journal.pone.0170076