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Role for Egr1 in the Transcriptional Program Associated with Neuronal Differentiation of PC12 Cells
PC12 cells are a well-established model to study how differences in signal transduction duration can elicit distinct cell behaviors. Epidermal growth factor (EGF) activates transient ERK signaling in PC12 cells that lasts 30–60 min, which in turn promotes proliferation; nerve growth factor (NGF) act...
Autores principales: | Adams, Kenneth W., Kletsov, Sergey, Lamm, Ryan J., Elman, Jessica S., Mullenbrock, Steven, Cooper, Geoffrey M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226839/ https://www.ncbi.nlm.nih.gov/pubmed/28076410 http://dx.doi.org/10.1371/journal.pone.0170076 |
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