The CCR2 Inhibitor Propagermanium Attenuates Diet-Induced Insulin Resistance, Adipose Tissue Inflammation and Non-Alcoholic Steatohepatitis

BACKGROUND AND AIM: Obese patients with chronic inflammation in white adipose tissue (WAT) have an increased risk of developing non-alcoholic steatohepatitis (NASH). The C-C chemokine receptor-2 (CCR2) has a crucial role in the recruitment of immune cells to WAT and liver, thereby promoting the infl...

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Detalles Bibliográficos
Autores principales: Mulder, Petra, van den Hoek, Anita M., Kleemann, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226841/
https://www.ncbi.nlm.nih.gov/pubmed/28076416
http://dx.doi.org/10.1371/journal.pone.0169740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226841/
https://www.ncbi.nlm.nih.gov/pubmed/28076416
http://dx.doi.org/10.1371/journal.pone.0169740

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