Propranolol, a β-adrenoceptor antagonist, worsens liver injury in a model of non-alcoholic steatohepatitis

Prazosin an α1-adrenoceptor (AR) antagonist has been shown to reduce liver injury in a mouse model of non-alcoholic steatohepatitis (NASH) and is suggested as a potential treatment of NASH especially given its concomitant anti-fibrotic properties. The effect however, of β-AR blockade in non-cirrhoti...

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Detalles Bibliográficos
Autores principales: McKee, Chad, Soeda, Junpei, Asilmaz, Esra, Sigalla, Barbara, Morgan, Maelle, Sinelli, Nicoletta, Roskams, Tania, Oben, Jude A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226920/
https://www.ncbi.nlm.nih.gov/pubmed/23850676
http://dx.doi.org/10.1016/j.bbrc.2013.07.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226920/
https://www.ncbi.nlm.nih.gov/pubmed/23850676
http://dx.doi.org/10.1016/j.bbrc.2013.07.005

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