Generation of a Spindle Checkpoint Arrest from Synthetic Signaling Assemblies

The spindle checkpoint acts as a mitotic surveillance system, monitoring interactions between kinetochores and spindle microtubules and ensuring high-fidelity chromosome segregation [1, 2, 3]. The checkpoint is activated by unattached kinetochores, and Mps1 kinase phosphorylates KNL1 on conserved ME...

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Detalles Bibliográficos
Autores principales: Yuan, Ivan, Leontiou, Ioanna, Amin, Priya, May, Karen M., Soper Ní Chafraidh, Sadhbh, Zlámalová, Eliška, Hardwick, Kevin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226922/
https://www.ncbi.nlm.nih.gov/pubmed/28017606
http://dx.doi.org/10.1016/j.cub.2016.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226922/
https://www.ncbi.nlm.nih.gov/pubmed/28017606
http://dx.doi.org/10.1016/j.cub.2016.11.014

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