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Fixed Versus Variable Dosing of Prothrombin Complex Concentrate in Vitamin K Antagonist-Related Intracranial Hemorrhage: A Retrospective Analysis

BACKGROUND: Millions of patients receive vitamin K antagonist (VKA) therapy worldwide. Annually 0.2–1 % of all VKA users develops an intracranial hemorrhage (ICH). Prothrombin complex concentrate (PCC) is administered to restore the INR ≤ 1.5 in an attempt to limit hematoma growth. In order to facil...

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Detalles Bibliográficos
Autores principales: Abdoellakhan, Rahat Amadkhan, Miah, Ishita Parveen, Khorsand, Nakisa, Meijer, Karina, Jellema, Korné
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5226998/
https://www.ncbi.nlm.nih.gov/pubmed/27052728
http://dx.doi.org/10.1007/s12028-016-0248-8