NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation

How neuronal proteomes self-organize is poorly understood because of their inherent molecular and cellular complexity. Here, focusing on mammalian synapses we use blue-native PAGE and ‘gene-tagging' of GluN1 to report the first biochemical purification of endogenous NMDA receptors (NMDARs) dire...

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Detalles Bibliográficos
Autores principales: Frank, René A. W., Komiyama, Noboru H., Ryan, Tomás J., Zhu, Fei, O'Dell, Thomas J., Grant, Seth G. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227094/
https://www.ncbi.nlm.nih.gov/pubmed/27117477
http://dx.doi.org/10.1038/ncomms11264