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NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation
How neuronal proteomes self-organize is poorly understood because of their inherent molecular and cellular complexity. Here, focusing on mammalian synapses we use blue-native PAGE and ‘gene-tagging' of GluN1 to report the first biochemical purification of endogenous NMDA receptors (NMDARs) dire...
Autores principales: | Frank, René A. W., Komiyama, Noboru H., Ryan, Tomás J., Zhu, Fei, O'Dell, Thomas J., Grant, Seth G. N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227094/ https://www.ncbi.nlm.nih.gov/pubmed/27117477 http://dx.doi.org/10.1038/ncomms11264 |
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