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Daphnetin Protects against Cerebral Ischemia/Reperfusion Injury in Mice via Inhibition of TLR4/NF-κB Signaling Pathway

Growing evidences indicate that immune-mediated mechanisms contribute to the development of cerebral ischemia/reperfusion (I/R) injury. Daphnetin (DAP) is a coumarin derivative extracted from Daphne odora var., which displays anti-inflammatory properties. However, the effect of DAP on cerebral I/R i...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Chen, Qianxue, Jian, Zhihong, Xiong, Xiaoxing, Shao, Lingmin, Jin, Tong, Zhu, Xiqun, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227117/
https://www.ncbi.nlm.nih.gov/pubmed/28119924
http://dx.doi.org/10.1155/2016/2816056