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Precise assembly and regulation of 26S proteasome and correlation between proteasome dysfunction and neurodegenerative diseases
Neurodegenerative diseases (NDs) often involve the formation of abnormal and toxic protein aggregates, which are thought to be the primary factor in ND occurrence and progression. Aged neurons exhibit marked increases in aggregated protein levels, which can lead to increased cell death in specific b...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Biochemistry and Molecular Biology
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227139/ https://www.ncbi.nlm.nih.gov/pubmed/27312603 http://dx.doi.org/10.5483/BMBRep.2016.49.9.094 |