Suppression of Akt-HIF-1α signaling axis by diacetyl atractylodiol inhibits hypoxia-induced angiogenesis

Hypoxia-inducible factor (HIF)-1α is a key regulator associated with tumorigenesis, angiogenesis, and metastasis. HIF-1α regulation under hypoxia has been highlighted as a promising therapeutic target in angiogenesis-related diseases. Here, we demonstrate that diacetyl atractylodiol (DAA) from Atrac...

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Detalles Bibliográficos
Autores principales: Choi, Sik-Won, Lee, Kwang-Sik, Lee, Jin Hwan, Kang, Hyeon Jung, Lee, Mi Ja, Kim, Hyun Young, Park, Kie-In, Kim, Sun-Lim, Shin, Hye Kyoung, Seo, Woo Duck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227144/
https://www.ncbi.nlm.nih.gov/pubmed/27439603
http://dx.doi.org/10.5483/BMBRep.2016.49.9.069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227144/
https://www.ncbi.nlm.nih.gov/pubmed/27439603
http://dx.doi.org/10.5483/BMBRep.2016.49.9.069

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