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Oct4 resetting by Aurkb–PP1 cell cycle axis determines the identity of mouse embryonic stem cells
In embryonic stem cells (ESCs), cell cycle regulation is deeply connected to pluripotency. Especially, core transcription factors (CTFs) which are essential to maintaining the pluripotency transcription programs should be reset during M/G1 transition. However, it remains unknown about how CTFs are g...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227292/ https://www.ncbi.nlm.nih.gov/pubmed/27697110 http://dx.doi.org/10.5483/BMBRep.2016.49.10.161 |