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Oct4 resetting by Aurkb–PP1 cell cycle axis determines the identity of mouse embryonic stem cells

In embryonic stem cells (ESCs), cell cycle regulation is deeply connected to pluripotency. Especially, core transcription factors (CTFs) which are essential to maintaining the pluripotency transcription programs should be reset during M/G1 transition. However, it remains unknown about how CTFs are g...

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Detalles Bibliográficos
Autores principales: Shin, Jihoon, Youn, Hong-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227292/
https://www.ncbi.nlm.nih.gov/pubmed/27697110
http://dx.doi.org/10.5483/BMBRep.2016.49.10.161