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Cordycepin inhibits chondrocyte hypertrophy of mesenchymal stem cells through PI3K/Bapx1 and Notch signaling pathway

Mesenchymal stem cells (MSCs) are widely used in cartilage tissue engineering to repair articular cartilage defects. However, hypertrophy of chondrocytes derived from MSCs might hinder the stabilization of hyaline cartilage. Thus, it is very important to find a suitable way to maintain the chondroge...

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Detalles Bibliográficos
Autores principales: Cao, Zhen, Dou, Ce, Li, Jianmei, Tang, Xiangyu, Xiang, Junyu, Zhao, Chunrong, Zhu, Lingyu, Bai, Yun, Xiang, Qiang, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227296/
https://www.ncbi.nlm.nih.gov/pubmed/27439604
http://dx.doi.org/10.5483/BMBRep.2016.49.10.071