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Histone H4 is cleaved by granzyme A during staurosporine-induced cell death in B-lymphoid Raji cells

Granzyme A (GzmA) was first identified as a cytotoxic T lymphocyte protease protein with limited tissue expression. A number of cellular proteins are known to be cleaved by GzmA, and its function is to induce apoptosis. Histones H1, H2B, and H3 were identified as GzmA substrates during apoptotic cel...

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Detalles Bibliográficos
Autores principales: Lee, Phil Young, Park, Byoung Chul, Chi, Seung Wook, Bae, Kwang-Hee, Kim, Sunhong, Cho, Sayeon, Kang, Seongman, Kim, Jeong-Hoon, Park, Sung Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227298/
https://www.ncbi.nlm.nih.gov/pubmed/27439606
http://dx.doi.org/10.5483/BMBRep.2016.49.10.105