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Enhancement of UV-induced nucleotide excision repair activity upon forskolin treatment is cell growth-dependent

Forskolin (FSK), an adenylyl cyclase activator, has recently been shown to enhance nucleotide excision repair (NER) upon UV exposure. However, our study revealed that this effect was detected in human skin epithelial ARPE19 cells only in growing cells, but not in non-cycling cells. When the cells we...

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Detalles Bibliográficos
Autores principales: Lee, Jeong-Min, Park, Jeong-Min, Kang, Tae-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227299/
https://www.ncbi.nlm.nih.gov/pubmed/27470212
http://dx.doi.org/10.5483/BMBRep.2016.49.10.097