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Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1

Our previous studies have demonstrated that erectile function was preserved in aged transgenic rats (TGR) harboring the human tissue kallikrein 1 (hKLK1), while the molecular level of hKLK1 on corporal fibrosis to inhibit age-related erectile dysfunction (ED) is poorly understood. Male wild-type Spr...

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Detalles Bibliográficos
Autores principales: Cui, Kai, Luan, Yang, Wang, Tao, Zhuan, Li, Rao, Ke, Wang, Shao-Gang, Ye, Zhang-Qun, Liu, Ji-Hong, Wang, Dao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227678/
https://www.ncbi.nlm.nih.gov/pubmed/27678468
http://dx.doi.org/10.4103/1008-682X.189209