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NF-κB activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection

Tolerance to bacterial components represents an essential regulatory mechanism during bacterial infection. Bacterial lipoprotein (BLP)-induced tolerance confers protection against microbial sepsis by attenuating inflammatory responses and augmenting antimicrobial activity in innate phagocytes. It ha...

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Detalles Bibliográficos
Autores principales: Liu, Jinghua, Xiang, Jing, Li, Xue, Blankson, Siobhan, Zhao, Shuqi, Cai, Junwei, Jiang, Yong, Redmond, H. Paul, Wang, Jiang Huai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227741/
https://www.ncbi.nlm.nih.gov/pubmed/28079153
http://dx.doi.org/10.1038/srep40418