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Denosumab treatment of inoperable or locally advanced giant cell tumor of bone

Giant cell tumor of bone (GCTB) is an osteolytic, locally aggressive tumor that rarely metastasizes and typically occurs in the bones. At present, the primary treatment for GCTB is curettage with local adjuvants. Giant cells express receptor activator of nuclear factor-κB ligand (RANKL). Denosumab,...

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Detalles Bibliográficos
Autores principales: Borkowska, Aneta, Goryń, Tomasz, Pieńkowski, Andrzej, Wągrodzki, Michał, Jagiełło-Wieczorek, Ewelina, Rogala, Paweł, Szacht, Milena, Rutkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228072/
https://www.ncbi.nlm.nih.gov/pubmed/28101196
http://dx.doi.org/10.3892/ol.2016.5246