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Anticancer effects of valproic acid on oral squamous cell carcinoma via SUMOylation in vivo and in vitro
Aberrant histone deacetylase (HDAC) has a key role in the neoplastic process associated with the epigenetic patterns of tumor-related genes. The present study was performed to investigate the effects and determine the mechanism of action of the HDAC inhibitor, valproic acid (VPA), on the CAL27 cell...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228083/ https://www.ncbi.nlm.nih.gov/pubmed/28101176 http://dx.doi.org/10.3892/etm.2016.3907 |