Cargando…

Anticancer effects of valproic acid on oral squamous cell carcinoma via SUMOylation in vivo and in vitro

Aberrant histone deacetylase (HDAC) has a key role in the neoplastic process associated with the epigenetic patterns of tumor-related genes. The present study was performed to investigate the effects and determine the mechanism of action of the HDAC inhibitor, valproic acid (VPA), on the CAL27 cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sang, Zhijian, Sun, Yang, Ruan, Hong, Cheng, Yong, Ding, Xiaojun, Yu, Youcheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228083/ https://www.ncbi.nlm.nih.gov/pubmed/28101176 http://dx.doi.org/10.3892/etm.2016.3907

Ejemplares similares

Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression
por: Terranova-Barberio, Manuela, et al.
Publicado: (2015)

Comparison of Anticancer Effects of Carbamazepine and Valproic Acid
por: Akbarzadeh, Ladan, et al.
Publicado: (2016)

HDAC inhibitor valproic acid upregulates CAR in vitro and in vivo
por: Segura-Pacheco, Blanca, et al.
Publicado: (2007)

In Vitro and In Vivo Radiosensitizing Effect of Valproic Acid on Fractionated Irradiation
por: Chie, Eui Kyu, et al.
Publicado: (2015)

KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition
por: Ding, Xiaojun, et al.
Publicado: (2017)

Quantitative in vitro to in vivo extrapolation for developmental toxicity potency of valproic acid analogues
por: Chang, Xiaoqing, et al.
Publicado: (2022)

In Vitro and in Vivo Anticancer Activity of Pardaxin against Proliferation and Growth of Oral Squamous Cell Carcinoma
por: Han, Yifan, et al.
Publicado: (2015)

Comparative in vivo bioequivalence and in vitro dissolution of two valproic acid sustained-release formulations
por: Fujii, Akira, et al.
Publicado: (2009)

Inhibitory effect of valproic acid on bladder cancer in combination with chemotherapeutic agents in vitro and in vivo
por: WANG, DEGUI, et al.
Publicado: (2013)

Valproic Acid Synergizes With Cisplatin and Cetuximab in vitro and in vivo in Head and Neck Cancer by Targeting the Mechanisms of Resistance
por: Iannelli, Federica, et al.
Publicado: (2020)

Pretreatment with valproic acid alleviates pulmonary fibrosis through epithelial–mesenchymal transition inhibition in vitro and in vivo
por: Chen, Lin, et al.
Publicado: (2021)

Anticancer Effects of Valproic Acid via Regulation of Epigenetic Mechanisms in Non-small-cell Lung Cancer A549 Cell Line
por: Kalantar, Hadi, et al.
Publicado: (2021)

Ginkgolic Acid, a SUMO-1 Inhibitor, Inhibits the Progression of Oral Squamous Cell Carcinoma by Alleviating SUMOylation of SMAD4
por: Liu, Ke, et al.
Publicado: (2019)

Effects of the Histone Deacetylase Inhibitor Valproic Acid on Human Pericytes In Vitro
por: Karén, Jakob, et al.
Publicado: (2011)

Angioedema induced by valproic acid
por: Yildiz, Sevler, et al.
Publicado: (2021)

In vitro anticancer activity of a pentacyclic triterpenoid via the mitochondrial pathway in bone-invasive oral squamous cell carcinoma
por: Adtani, Pooja Narain, et al.
Publicado: (2021)

Valproic Acid Induces Cutaneous Wound Healing In Vivo and Enhances Keratinocyte Motility
por: Lee, Soung-Hoon, et al.
Publicado: (2012)

The possibility of healing alveolar bone defects with simvastatin thermosensitive gel: in vitro/in vivo evaluation
por: Ruan, Hong, et al.
Publicado: (2018)

Lamin A/C Mutants Disturb Sumo1 Localization and Sumoylation in Vitro and in Vivo
por: Boudreau, Émilie, et al.
Publicado: (2012)

Histone deacetylase inhibitor, valproic acid, radiosensitizes the C6 glioma cell line in vitro
por: ZHOU, YONG, et al.
Publicado: (2014)

Expression and Prognosis Analysis of SUMOylation Regulators in Oral Squamous Cell Carcinoma Based on High-Throughput Sequencing
por: Meng, Yutong, et al.
Publicado: (2021)

Effects of valproic acid on histone deacetylase inhibition in vitro and in glioblastoma patient samples
por: Berendsen, Sharon, et al.
Publicado: (2019)

Valproic acid-induced abnormal behavior
por: Nagalakshmi, Nanjangud Chandrashekar, et al.
Publicado: (2010)

Assessing hepatotoxicity of valproic acid in Dictyostelium
Publicado: (2012)

Hyperammonemia Associated with Valproic Acid Concentrations
por: Vázquez, Marta, et al.
Publicado: (2014)

Valproic acid-induced acute pancreatitis
por: Jain, Ayush, et al.
Publicado: (2019)

On the Digital Psychopharmacology of Valproic Acid in Mice
por: Bass, John Samuel, et al.
Publicado: (2020)

Severe Pancytopenia Induced by Valproic Acid
por: Wahba, Andrew, et al.
Publicado: (2020)

Acute pancreatitis induced by valproic acid
por: Khouadja, S., et al.
Publicado: (2021)

Kava constituents exert selective anticancer effects in oral squamous cell carcinoma cells in vitro
por: Celentano, Antonio, et al.
Publicado: (2020)

Commonly Prescribed Anticoagulants Exert Anticancer Effects in Oral Squamous Cell Carcinoma Cells In Vitro
por: Ling, Li-Qiao R., et al.
Publicado: (2022)

Valproic acid protects against haemorrhagic shock‐induced signalling changes via PPARγ activation in an in vitro model
por: Zuckermann, Alexandra M E, et al.
Publicado: (2015)

Valproic Acid Enhanced Temozolomide-Induced Anticancer Activity in Human Glioma Through the p53–PUMA Apoptosis Pathway
por: Tsai, Hong-Chieh, et al.
Publicado: (2021)

Metabolomic profiling of triple negative breast cancer cells suggests that valproic acid can enhance the anticancer effect of cisplatin
por: Granit, Avital, et al.
Publicado: (2022)

Effect of Short-Term Oral Valproic Acid on Vision and Visual Field in Retinitis Pigmentosa
por: Shanmugam, P. Mahesh, et al.
Publicado: (2012)

Valproic acid prevents glucocorticoid-induced osteonecrosis of the femoral head of rats
por: Zhou, Ding, et al.
Publicado: (2018)

Impact of valproic acid on busulfan pharmacokinetics: In vitro assessment of potential drug-drug interaction
por: Al-Enezi, Bashayer F., et al.
Publicado: (2023)

Effects of amoxicillin/clavulanic acid on the pharmacokinetics of valproic acid
por: Lee, Soo-Yun, et al.
Publicado: (2015)

The In Vitro and In Vivo Antitumor Effects of Clotrimazole on Oral Squamous Cell Carcinoma
por: Wang, Juan, et al.
Publicado: (2014)

In vitro and in vivo antitumor effects of chloroquine on oral squamous cell carcinoma
por: Jia, Lihua, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p9bqkqbqmrqmaeogqd9itubjrj