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Non-linear impact of glutathione depletion on C. elegans life span and stress resistance

The redox environment in cells and organisms is set by low-molecular mass and protein-bound thiols, with glutathione (GSH) representing a major intracellular redox buffer. Subtle thiol oxidation elicits signal transduction processes and adaptive responses to cope with stressors, whereas highly oxidi...

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Detalles Bibliográficos
Autores principales: Urban, Nadine, Tsitsipatis, Dimitrios, Hausig, Franziska, Kreuzer, Katrin, Erler, Katrin, Stein, Vanessa, Ristow, Michael, Steinbrenner, Holger, Klotz, Lars-Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228094/
https://www.ncbi.nlm.nih.gov/pubmed/28086197
http://dx.doi.org/10.1016/j.redox.2016.12.003