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Emerging links between m(6)A and misregulated mRNA methylation in cancer

N (6)-methyladenosine (m(6)A) in mRNA has emerged as a crucial epitranscriptomic modification that controls cellular differentiation and pluripotency. Recent studies are pointing to a role for the RNA methylation program in cancer self-renewal and cell fate, making this a new and promising therapeut...

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Detalles Bibliográficos
Autores principales: Jaffrey, Samie R., Kharas, Michael G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228104/
https://www.ncbi.nlm.nih.gov/pubmed/28081722
http://dx.doi.org/10.1186/s13073-016-0395-8