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Diosmetin triggers cell apoptosis by activation of the p53/Bcl-2 pathway and inactivation of the Notch3/NF-κB pathway in HepG2 cells

Diosmetin (DIOS), a flavonoid compound, is abundant in Citrus limon. Emerging studies have shown that DIOS is an effective compound implicated in multiple types of cancer. However, whether DIOS serves a role in hepatocellular carcinoma (HCC) is still obscure. HepG2 cells were used in the present stu...

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Detalles Bibliográficos
Autores principales: Qiao, Jie, Liu, Jie, Jia, Kaiqiao, Li, Ning, Liu, Bin, Zhang, Qingyu, Zhu, Runzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228289/
https://www.ncbi.nlm.nih.gov/pubmed/28101238
http://dx.doi.org/10.3892/ol.2016.5347