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Interferon-γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission

BACKGROUND: Malaria elimination campaigns are planned or active in many countries. The effects of malaria elimination on immune responses such as antigen-specific IFN- γ responses are not well characterized. METHODS: IFN- γ responses to the P. falciparum antigens circumsporozoite protein, liver stag...

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Detalles Bibliográficos
Autores principales: Ayieko, Cyrus, Ogola, Bilha S., Ochola, Lyticia, Ngwena, Gideon A.M., Ayodo, George, Hodges, James S., Noland, Gregory S., John, Chandy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228499/
https://www.ncbi.nlm.nih.gov/pubmed/28097063
http://dx.doi.org/10.7717/peerj.2855