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RNA interference targeting Aurora-A sensitizes glioblastoma cells to temozolomide chemotherapy

Clinically, temozolomide (TMZ) is widely used in glioblastoma (GBM) treatment. However, the toxicity of TMZ may influence the quality of patient life. Thus, novel treatment options for sensitizing GBM cells to TMZ chemotherapy are necessary. Aurora-A is widely expressed in GBM and correlated with po...

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Detalles Bibliográficos
Autores principales: Gan, Jing, Wang, Fangfang, Mu, Dezhi, Qu, Yi, Luo, Rong, Wang, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228570/
https://www.ncbi.nlm.nih.gov/pubmed/28105161
http://dx.doi.org/10.3892/ol.2016.5261