Comprehensive assessment of estrogen receptor beta antibodies in cancer cell line models and tissue reveals critical limitations in reagent specificity

Estrogen Receptor-β (ERβ) has been implicated in many cancers. In prostate and breast cancer its function is controversial, but genetic studies implicate a role in cancer progression. Much of the confusion around ERβ stems from antibodies that are inadequately validated, yet have become standard too...

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Detalles Bibliográficos
Autores principales: Nelson, Adam W., Groen, Arnoud J., Miller, Jodi L., Warren, Anne Y., Holmes, Kelly A., Tarulli, Gerard A., Tilley, Wayne D., Katzenellenbogen, Benita S., Hawse, John R., Gnanapragasam, Vincent J., Carroll, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228587/
https://www.ncbi.nlm.nih.gov/pubmed/27889472
http://dx.doi.org/10.1016/j.mce.2016.11.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228587/
https://www.ncbi.nlm.nih.gov/pubmed/27889472
http://dx.doi.org/10.1016/j.mce.2016.11.016

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