Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms

People with Type 2 diabetes mellitus (T2DM) have reduced bone mineral density and an increased risk of fractures due to altered mesenchymal stem cell (MSC) differentiation in the bone marrow. This leads to a shift in the balance of differentiation away from bone formation (osteogenesis) in favour of...

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Detalles Bibliográficos
Autores principales: Chen, Suet Ching, Brooks, Rebecca, Houskeeper, Jessica, Bremner, Shaun K., Dunlop, Julia, Viollet, Benoit, Logan, Pamela J., Salt, Ian P., Ahmed, S. Faisal, Yarwood, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: North Holland Publishing 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228588/
https://www.ncbi.nlm.nih.gov/pubmed/27856330
http://dx.doi.org/10.1016/j.mce.2016.11.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228588/
https://www.ncbi.nlm.nih.gov/pubmed/27856330
http://dx.doi.org/10.1016/j.mce.2016.11.011

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