Increasing LAG-3 expression suppresses T-cell function in chronic hepatitis B: A balance between immunity strength and liver injury extent

Weak or absent virus-specific CD8(+) T-cell responses to hepatitis B virus (HBV) infection are thought to be responsible for persistent HBV infection. Previous studies have indicated that multiple inhibitory receptors, including lymphocyte activation gene-3 (LAG-3), can suppress the CD8(+) T-cell re...

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Detalles Bibliográficos
Autores principales: Ye, Bo, Li, Xuefen, Dong, Yuejiao, Wang, Yiyin, Tian, Li, Lin, Sha, Liu, Xia, Kong, Haishen, Chen, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2017
Materias:
4500
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228642/
https://www.ncbi.nlm.nih.gov/pubmed/28072682
http://dx.doi.org/10.1097/MD.0000000000005275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5228642/
https://www.ncbi.nlm.nih.gov/pubmed/28072682
http://dx.doi.org/10.1097/MD.0000000000005275

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