MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter

Non-invasive imaging of gene expression can be used to track implanted cells in vivo but often requires the addition of an exogenous contrast agent that may have limited tissue access1. We show that the urea transporter (UT-B) can be used as a gene reporter, where reporter expression was detected us...

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Detalles Bibliográficos
Autores principales: Schilling, Franz, Ros, Susana, Hu, De-En, D'Santos, Paula, McGuire, Sarah, Mair, Richard, Wright, Alan J., Mannion, Elizabeth, Franklin, Robin J. M., Neves, André A., Brindle, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230773/
https://www.ncbi.nlm.nih.gov/pubmed/27918546
http://dx.doi.org/10.1038/nbt.3714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230773/
https://www.ncbi.nlm.nih.gov/pubmed/27918546
http://dx.doi.org/10.1038/nbt.3714

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