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Dermal γδ T Cells Do Not Freely Re-Circulate Out of Skin and Produce IL-17 to Promote Neutrophil Infiltration during Primary Contact Hypersensitivity

The role of mouse dermal γδ T cells in inflammatory skin disorders and host defense has been studied extensively. It is known that dendritic epidermal T cells (DETC) have a monomorphic γδ T cell receptor (TCR) and reside in murine epidermis from birth. We asked if dermal γδ cells freely re-circulate...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaodong, Park, Chang Ook, Geddes Sweeney, Jenna, Yoo, Min Jae, Gaide, Olivier, Kupper, Thomas Seth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5230790/
https://www.ncbi.nlm.nih.gov/pubmed/28081153
http://dx.doi.org/10.1371/journal.pone.0169397