Identifying Pleiotropic Genes in Genome-Wide Association Studies for Multivariate Phenotypes with Mixed Measurement Scales

We propose a multivariate genome-wide association test for mixed continuous, binary, and ordinal phenotypes. A latent response model is used to estimate the correlation between phenotypes with different measurement scales so that the empirical distribution of the Fisher’s combination statistic under...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, James J., Williams, L. Keoki, Buu, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231271/
https://www.ncbi.nlm.nih.gov/pubmed/28081206
http://dx.doi.org/10.1371/journal.pone.0169893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231271/
https://www.ncbi.nlm.nih.gov/pubmed/28081206
http://dx.doi.org/10.1371/journal.pone.0169893

Ejemplares similares