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T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice

BACKGROUND: Ragweed (Ambrosia artemisiifolia) and mugwort (Artemisia vulgaris) are the major cause of pollen allergy in late summer. Allergen-specific lymphocytes are crucial for immune modulation during immunotherapy. We sought to generate and pre-clinically characterise highly immunogenic domains...

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Detalles Bibliográficos
Autores principales: Sancho, Ana I., Wallner, Michael, Hauser, Michael, Nagl, Birgit, Himly, Martin, Asam, Claudia, Ebner, Christof, Jahn-Schmid, Beatrice, Bohle, Barbara, Ferreira, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231356/
https://www.ncbi.nlm.nih.gov/pubmed/28081194
http://dx.doi.org/10.1371/journal.pone.0169784