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Fcγ-receptor IIa-mediated Src Signaling Pathway Is Essential for the Antibody-Dependent Enhancement of Ebola Virus Infection

Antibody-dependent enhancement (ADE) of Ebola virus (EBOV) infection has been demonstrated in vitro, raising concerns about the detrimental potential of some anti-EBOV antibodies. ADE has been described for many viruses and mostly depends on the cross-linking of virus-antibody complexes to cell surf...

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Detalles Bibliográficos
Autores principales: Furuyama, Wakako, Marzi, Andrea, Carmody, Aaron B., Maruyama, Junki, Kuroda, Makoto, Miyamoto, Hiroko, Nanbo, Asuka, Manzoor, Rashid, Yoshida, Reiko, Igarashi, Manabu, Feldmann, Heinz, Takada, Ayato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231391/
https://www.ncbi.nlm.nih.gov/pubmed/28036370
http://dx.doi.org/10.1371/journal.ppat.1006139