Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques

Poor maintenance of cytotoxic factor expression among HIV-specific CD8+ T cells, in part caused by dysregulated expression of the transcription factor T-bet, is associated with HIV disease progression. However, the precise evolution and context in which CD8+ T cell cytotoxic functions become dysregu...

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Detalles Bibliográficos
Autores principales: Roberts, Emily R., Carnathan, Diane G., Li, Hui, Shaw, George M., Silvestri, Guido, Betts, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231392/
https://www.ncbi.nlm.nih.gov/pubmed/28036372
http://dx.doi.org/10.1371/journal.ppat.1006135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5231392/
https://www.ncbi.nlm.nih.gov/pubmed/28036372
http://dx.doi.org/10.1371/journal.ppat.1006135

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